Institut de la Vision
Delarasse Cécile
Inserm Researcher
Our team is interested in Inflammation and immunology in retinal diseases.
Réferences:
Déchelle-Marquet PA, Guillonneau X, Sennlaub F, Delarasse C.
P2X7-dependent immune pathways in retinal diseases.
Neuropharmacology. 2023 Feb 1; 223:109332. doi: 10.1016/j.neuropharm. 2022.109332.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, NeuroCEB Brain Bank, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D, Delarasse C. P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy. Prog Neurobiol. 2021 Aug 12:102139. doi: 10.1016/j.pneurobio.2021.102139
Douguet L, Janho Dit Hreich S, Benzaquen J, Seguin L, Juhel T, Dezitter X, Duranton C, Ryffel B, Kanellopoulos J, Delarasse C, Renault N, Furman C, Homerin G, Féral C, Cherfils-Vicini J, Millet R, Adriouch S, Ghinet A, Hofman P, Vouret-Craviari V. A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy. Nat Commun. 2021 Jan 28;12(1):653. doi: 10.1038/s41467-021-20912-2.
Kanellopoulos JM, Delarasse C. Pleiotropic Roles of P2X7 in the Central Nervous System. Front Cell Neurosci. 2019 Sep 4;13:401. doi: 10.3389/fncel.2019.00401
Martin E, Amar M, Dalle C, Youssef I, Boucher C, Le Duigou C, Brückner M, Prigent, A, Sazdovitch V, Halle A, Kanellopoulos JM, Fontaine B, Delatour B, Delarasse C. New role of P2X7 receptor in an Alzheimer’s disease mouse model. Mol Psychiatry. 2019 Jan;24(1):108-125. doi: 10.1038/s41380-018-0108-3.